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Thursday, July 3, 2025

Dr Rajini Haraksingh’s journey: From global genomics to local impact

by

Fayola K J Fraser
4 days ago
20250629

On any giv­en day, you might find Dr Ra­ji­ni Haraks­ingh walk­ing briskly through the cam­pus of The Uni­ver­si­ty of the West In­dies (UWI) in St Au­gus­tine, where she serves as a lec­tur­er in Biotech­nol­o­gy.

But long be­fore she joined the fac­ul­ty, the cam­pus was still her home base. The daugh­ter of two UWI lec­tur­ers—her fa­ther, Dr Kusha Haraks­ingh, a his­to­ri­an and lawyer, and her moth­er, Dr In­dra Haraks­ingh, a physi­cist with a fo­cus on re­new­able en­er­gy in the Caribbean—Haraks­ingh grew up im­mersed in aca­d­e­m­ic life.

Hav­ing been raised deeply root­ed in the bounds of the com­mu­ni­ty, at­tend­ing both UWI pri­ma­ry school and St Au­gus­tine Girls’ High School (SAGHS) near­by, Haraks­ingh’s world­view was nev­er small. “I’ve al­ways been a cit­i­zen of the world,” she says. “And I keen­ly knew there was more out there.”

That in­nate cu­rios­i­ty and dri­ve to ex­pand took Haraks­ingh to some of the most pres­ti­gious aca­d­e­m­ic in­sti­tu­tions in the world. She com­plet­ed her un­der­grad­u­ate de­gree in Math­e­mat­ics and Mol­e­c­u­lar Bi­ol­o­gy at the Mass­a­chu­setts In­sti­tute of Tech­nol­o­gy (MIT), spent a year abroad at Cam­bridge, and lat­er earned her MSc in Mol­e­c­u­lar Bi­ol­o­gy, PhD in Hu­man Ge­nomics at Yale Uni­ver­si­ty.

Her path was nev­er a straight one, as Haraks­ingh ex­plored a wide range of in­ter­ests—one of her proud­est mo­ments was be­ing named Best All-Round Stu­dent at SAGHS.

Cred­it­ing the sup­port­ive and in­tel­lec­tu­al­ly vi­brant house­hold she grew up in, she says, “My par­ents nev­er pi­geon-holed my in­ter­ests. I did swim­ming, danc­ing, Math Olympiad, and all my in­ter­ests were nur­tured.” In fact, it was this free­dom to ex­plore all facets of the hu­man ex­pe­ri­ence that led her to her pas­sion–ex­am­in­ing and learn­ing more about life it­self.

Re­mem­ber­ing her jour­ney in­to ge­nomics, she felt it was her “in­nate cu­rios­i­ty, and de­sire to un­der­stand things, cou­pled with the re­al­i­sa­tion that I cared about life and want­ed to un­der­stand life at the most fun­da­men­tal lev­el,” that led her away from her ini­tial in­ter­est in study­ing physics.

Her ex­pe­ri­ence in ge­nomics be­gan at a time when the world of bi­ol­o­gy was un­der­go­ing a rev­o­lu­tion. “When I start­ed un­der­grad, the hu­man genome had just been se­quenced,” she ex­plains. “It was the first time in hu­man his­to­ry that we could read the in­struc­tion book of what makes us hu­man.” That mo­ment of sci­en­tif­ic awak­en­ing led her to progress to the study of vari­a­tion in hu­man genomes dur­ing her PhD, ul­ti­mate­ly join­ing the 1000 Genomes Project—a mas­sive glob­al col­lab­o­ra­tion in­volv­ing over 500 sci­en­tists which she de­scribes as a ca­reer high­light.

“We were able to char­ac­terise how di­verse peo­ple re­al­ly are, ge­net­i­cal­ly,” she says, re­mem­ber­ing the 1,000 Genomes Project. “It laid the ground­work for un­der­stand­ing how pop­u­la­tions, in­clud­ing Caribbean ones, have evolved and why they may be more sus­cep­ti­ble to con­di­tions like di­a­betes or heart dis­ease.”

Her par­tic­i­pa­tion in this project, among oth­ers, al­lowed her to in­cor­po­rate Caribbean peo­ple and the re­gion­al hu­man ex­pe­ri­ence in places where they may have tra­di­tion­al­ly been over­looked.

Her ca­reer flour­ish­ing abroad, Haraks­ingh was at the top of her field re­search­ing and work­ing in top-class in­sti­tu­tions. She al­ways knew, how­ev­er, that she want­ed to make sig­nif­i­cant con­tri­bu­tions lo­cal­ly, “in­ter­est­ed in en­sur­ing that my ef­forts ben­e­fit­ed this re­gion.” In 2015, af­ter 14 years over­seas, she ac­cept­ed what she de­scribed as her “dream job” at UWI, St Au­gus­tine, and was tasked with sup­port­ing the build-out of new biotech­nol­o­gy pro­grammes.

Aside from her de­sire to con­tribute, she says, “I didn’t want to just work in a place that nev­er shuts off. Trinidad has this cel­e­bra­to­ry, warm, and fes­tive air.”

Her re­turn in 2015 al­so co­in­cid­ed with a grow­ing glob­al recog­ni­tion of the im­por­tance of study­ing di­verse pop­u­la­tions—and she felt com­pelled to ap­ply her work abroad and re­search to T&T.

Her work has al­ready made an in­deli­ble im­pact. In one of her most sig­nif­i­cant achieve­ments, Haraks­ingh se­cured a grant from the In­ter­na­tion­al Cen­tre for Ge­net­ic En­gi­neer­ing and Biotech­nol­o­gy to in­ves­ti­gate the ge­net­ics of Di­a­betes in the pop­u­la­tion of Caribbean in­di­vid­u­als.

“That was a re­al ca­reer high­light,” she says, al­so ac­knowl­edg­ing the chal­lenges she faced get­ting ap­provals and get­ting the study off the ground. “It val­i­dat­ed the im­por­tance of study­ing our own pop­u­la­tions, and un­der­stand­ing the unique­ness of our bi­ol­o­gy at play.”

She ex­pects that this work will scratch the sur­face of a deep­er in­ves­ti­ga­tion in­to the ge­net­ic ae­ti­ol­o­gy of di­a­betes in the Trinida­di­an pop­u­la­tion, with the re­sults be­ing able to in­form the de­sign of clin­i­cal screen­ing pan­els for this pop­u­la­tion as well as in oth­er sim­i­lar pop­u­la­tions in the wider Caribbean.

For over a decade, she has been in­stru­men­tal in build­ing lo­cal ca­pac­i­ty in biotech­nol­o­gy, launch­ing both un­der­grad­u­ate and post­grad­u­ate pro­grams—foun­da­tion­al work that paid div­i­dends dur­ing the COVID-19 pan­dem­ic.

Amidst her pro­fes­sion­al ac­com­plish­ments, Haraks­ingh has em­braced the trans­for­ma­tive ex­pe­ri­ence of par­ent­hood. Now a moth­er of two young boys, aged five and two, she finds her­self with a new­found ap­pre­ci­a­tion for her own par­ents.

“Be­ing a present, con­scious par­ent is so im­por­tant,” she re­flects. “It’s what builds a child’s con­fi­dence to take on the world.” Her par­ent­ing phi­los­o­phy, shared equal­ly with her hus­band—whom she jokes is “in charge of out­put while I’m in charge of in­put”—is root­ed in the same sense of com­mu­ni­ty she was raised in. “You can’t do it alone. My par­ents who are now de­vot­ed and in­volved grand­par­ents, my aunt, our babysit­ter, and my whole vil­lage have con­tributed to my suc­cess.”

Through it all, Haraks­ingh re­mains com­mit­ted to her per­son­al ethos: nev­er lim­it your­self. She sees dan­ger in not ex­plor­ing all in­ter­ests, av­enues, and per­son­al po­ten­tial, as “there is so much to like and ex­pe­ri­ence and it’s im­por­tant to ex­pe­ri­ence it all deeply.”

Dri­ven by an in­sa­tiable de­sire to know how things de­vel­op and why, she has emerged as a thought leader in her field and is break­ing ground for the ad­vance­ment of re­search and un­der­stand­ing of ge­net­ics in the re­gion.


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